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Duovir.
  Tablets Structure.

Duovir = Lamivudine 150mg and Zidovudine USP 300mg

  Usage.

Duovir is used for treatment of an infection of a HIV, as a part of a combination therapy.

  Recommended dosage.

Recommended oral dosage Duovir for adults and teenagers (at least 12 years of age) - one tablet (containing 150 mg lamivudine and 300 mg zidovudine) twice daily with or without the foodstuffs.
Regulation of the dosage: as it - the established combination of a dosage, Duovir should not, to be ordered for the patients demanding regulation of a dosage such as those with the reduced kidney function (carrying out of calculations creatinine <50 ml / minutes), those with low weight of a body (<50 kg or 110 pounds), or what test restriction of a dosage adverse events.

  Warnings and Precautions.

Duovir tablets are served by contra-indication in patients with preliminary shown clinically essential hypersensitivity to any of components of a product.

  Duovir-N Structure.

Duovir-N = Lamivudine 150mg, Zidovudine USP 300mg, Nevirapine 200mg

   Usage.

Duovir-N is used for treatment of an infection of a HIV as soon as patients have steady on a mode of service nevirapine a switching board on 200 mg, and showed adequate tolerability to nevirapine.

   Recommended Dosage.

Adults

1 tablet twice daily

Duovir-N should not cope to patients who have just started therapy with nevirapine. It-, because initial leadership - in a somnolence of 200 mg nevirapine once daily within 2 weeks it is recommended. After that leaderships - in the dosage, rise of a dosage (dosage of service) to 200 mg nevirapine a switching board can be it is executed in absence of any reactions of hypersensitivity (for example a rash, function of a liver checks deviations.

The control of patients

Clinical tests of chemistry which include tests of function of a liver, should be executed before introduction of leadership - in nevirapine therapies and in corresponding intervals during therapy.

Regulation of the Dosage

As it - a combination of an establish - dosage, Duovir-N should not be ordered for the patients demanding regulation of a dosage, such as those with a low body weight (<50 kg), the reduced kidney function (carrying out of calculations creatinine <50 ml / minutes) or what test adverse events limiting a dosage.
Duovir-N should be stopped, if patients test a serious rash or a the rash accompanied with the constitutional results. The patients testing moderate to decrease a rash during 14-day's leadership - during 200mg / days should not do not increase them nevirapine a dosage or therapy of the beginning with Duovir-N up to the rash has decided.
Duovir-N administration should be interrupted in overcoming patients decrease or serious function of a liver checks deviations (excluding GGT), while eminences of test of function of a liver have not come back to the basis. Nevirapine (using Nevimune Tablets) can then to be repeatedly started in 200mg day.
The increase in a daily dosage to 200 mg twice daily (using Duovir-N) should be made with caution, after the expanded supervision. Nevirapine should be constantly stopped if the moderate or serious liver functions test deviations come back.
Patients who interrupt nevirapine, dozing during more than 7 days, should begin repeatedly recommended somnolence, use of one of 200 mg Nevimune a tablet daily for first 14 days (leadership - â) in a combination with another antiretrovirals, accompanied on 200mg twice daily using Duovir-N in absence of any signatures hypersensitivity.
Harmed kidney and function of hepatic any data are not accessible to recommend a dosage nevirapine in patients with dysfunction hepatic, kidney lack or testing dialysis.

   Warnings and Precautions.

Duovir-N is served by contra-indication in patients with clinically essential hypersensitivity to any of the components containing in the formulation.
Duovir-N also is served by contra-indication for patients who only begin therapy with nevirapine. These patients demand leadership - in a dosage nevirapine 200 mg o.d. whereas this formulation contains a dosage of service nevirapine 200mg b.d.

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