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Metolar.
   Tablets/Injection Structure.

Metolar-25 = Metoprolol Tartrate IP 25mg
Metolar-50 = Metoprolol Tartrate IP 50mg
Metolar-100 = Metoprolol Tartrate IP 100mg
Metolar Injection 1 ml = Metoprolol Tartrate IP 1mg, Sodium Chloride IP 9mg and Water for injection q.s. 1ml

   Usage.

Hypertension, stenocardia, intimate arrhythmias, certain or suspected sharp heart attack of a myocardium, preventive maintenance of a migraine, hyperthyroidism and additional management thyrotoxicosis.

   Recommended dosage.

HYPERTENSION

Usual initial dose - 100 mg daily in the unique or divided doses. The dosage can be increased if it is necessary, up to an optimum blood pressure reduction is achieved.

STENOCARDIA

Usual initial dose - 100 mg, daily, the data in two divided doses. If necessary, the dosage can be increased in weekly intervals, up to an optimum the clinical answer has been received.

INTIMATE arrhythmias

Metolar tablets: a usual dose - 100-200 mg daily in the divided doses. If necessary, the dose can be increased.
Metolar the Injection: Originally up to 5 mg should be entered intravenously in a norm of 1-2 mg / minutes. The injection can be repeated in intervals of 5 minutes while the satisfactory answer has not been received. A full dose of 10-15 mg in general it appears sufficient. doses of 20 mg or more, hardly, will be terminated further therapeutic benefit.

HEART ATTACK OF THE MYOCARDIUM

Early Treatment: During an early stage certain or suspected sharp the heart attack of a myocardium, treatment with Metolar should be entered as soon as far as possible. Such treatment should be entered in coronary unit of care immediately after hemodynamic the condition of the patient stabilized.
Treatment in this early stage should begin intravenous administration of three injections of a ball of 5 mg metoprolol everyone; injections need to be given in approximately 2-minute intervals. During intravenous administration Metolar, a blood pressure, estimates heart and the electrocardiogram should be checked carefully up.
In patients who suppose a full intravenous dose (15 mg), Metolar tablets 50 mg each 6 hours, should be entered later 15 minutes after last intravenous the dose also proceeded within 48 hours. After that, patients should receive a dose of service of 100 mg twice daily. Patients who, apparently, do not suppose the full intravenous dose should be started on metoprolol or 25 mg or 50 mg each 6 hours (depending on a degree of intolerance) 15 minutes after last intravenous dose or as soon as their clinical condition allows.
In patients with serious intolerance, treatment with metoprolol should be Stopped.

Last treatment: Patients with contra-indications to treatment during early stage of the suspected or certain heart attack of a myocardium, patients who appear to not admit full early treatment, and patients in whom the doctor wishes to detain therapy for any other reason should be started on lower dose metoprolol as soon as their clinical condition allows. Therapy should be it is continued within at least 3 months. The data from studying with others beta blockers suggest, that treatment has been continued within 1-3 years.

HYPERTHYROIDISM

Usual dose - 150-200 mg daily, in 3-4 divided doses.

PREVENTIVE MAINTENANCE OF THE MIGRAINE

dose - 100-200 mg, daily the data in the divided doses.

THYROTOXICOSIS

Usual dose - 50 mg three or four once a day.

   Warnings and Precautions.

Bradycardia of the bosom, the second or third block of heart of a degree, cardiogenic shock, frank intimate refusal, patients of a heart attack of a myocardium with intimate norm <45 impacts / minutes, the essential first block of heart of a degree (P-R an interval 0.24 second), systolic a blood pressure <100 mm of Hg and-or moderate to serious intimate refusal.